IMMUNOLOGY

MISCELLENOUS

VACCINATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
White blood cells are immune cells that are present in blood and other tissues. Leukocytes have pattern recognition molecules that react to
A
toll-like receptors (TLRs)
B
leukocytes
C
pathogen-associated molecular patterns (PAMPs)
D
erythrocytes
Explanation: 

Detailed explanation-1: -PAMPs are derived from microorganisms and thus drive inflammation in response to infections. One well-known PAMP is lipopolysaccharide (LPS), which is found on the outer cell wall of gram-negative bacteria.

Detailed explanation-2: -Major PAMPs are nucleic acids, including DNA, dsRNA, ssRNA, and 5′-triphosphate RNA, as well as surface glycoproteins (GP), lipoproteins (LP), and membrane components (peptidoglycans [PG], lipoteichoic acid [LTA], LPS, and GPI anchors). These PAMPs are recognized by different families of PRRs.

Detailed explanation-3: -Pathogen associated molecular patterns (PAMP) are molecules with conserved motifs that are associated with pathogen infection that serve as ligands for host pattern recognition molecules such as Toll-like receptors.

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