IMMUNOLOGY

OVERVIEW OF THE IMMUNE SYSTEM

IMMUNITY INNATE AND ADAPTIVE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
____ become immunocompetent in the thymus and are NOT antibody producing.
A
B-lymphocytes
B
T-lymphocytes
C
monocytes
D
mast cells
Explanation: 

Detailed explanation-1: -B cells achieve immunocompetence (ability to recognize a specific antigen) in bone marrow. T cells migrate to the thymus gland, where they become immunocompetent. However, the lymphocytes are immature (not fully developed) and cannot directly participate in an immune response.

Detailed explanation-2: -T lymphocytes develop from a common lymphoid progenitor in the bone marrow that also gives rise to B lymphocytes, but those progeny destined to give rise to T cells leave the bone marrow and migrate to the thymus (see Fig. 7.2). This is the reason they are called thymus-dependent (T) lymphocytes or T cells.

Detailed explanation-3: -The thymus makes white blood cells called T lymphocytes. These are also called T cells. These are an important part of the body’s immune system, which helps to fight infection. The thymus gland grows to its largest size during childhood and makes all the T cells we need before we become teenagers.

Detailed explanation-4: -THE THYMUS IS A SPECIALIZED ORGAN THAT DIRECTS THE DEVELOPMENT AND SELECTION OF T CELLS WHICH DIRECT ADAPTIVE IMMUNITY.

Detailed explanation-5: -Lymphocyte There are two main types of lymphocytes: B cells and T cells. The B cells produce antibodies that are used to attack invading bacteria, viruses, and toxins. The T cells destroy the body’s own cells that have themselves been taken over by viruses or become cancerous.

Detailed explanation-6: -T cells comprise the largest percentage of lymphocytes. These cells originate in the bone marrow, and then migrate to the thymus to become immunocompetent, or activated. When properly stimulated, T cells differentiate into several different cell types that will attack antigens and increase the body’s immune response.

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