IMMUNOLOGY

Detailed explanation-1: -Phagocytosis consists in recognition and ingestion of particles larger than 0.5 m into a plasma membrane derived vesicle, known as phagosome. Phagocytes can ingest microbial pathogens, but importantly also apoptotic cells.

Detailed explanation-2: -Microglia are currently considered to be the major phagocytes in the brain parenchyma, and these cells phagocytose a variety of materials, including dead cell debris, abnormally aggregated proteins, and, interestingly, the functional synapses of living neurons.

Detailed explanation-3: -Macrophages and neutrophils display a variety of cell-surface receptors that enable them to recognize and engulf pathogens.

Detailed explanation-4: -Phagocytes are motile by ameboid action. Chemotaxis is movement of the cells in response to a chemical stimulus. The eventual concentration of phagocytes at a site of injury results from chemotactic response by the phagocytes which is analogous to bacterial chemotaxis.

Detailed explanation-5: -Macrophages and neutrophils (phagocytes) are the front-line defenders in your body’s immune system. They seek out, ingest, and destroy pathogens and other debris through a process called phagocytosis.

Detailed explanation-6: -In phagocytosis, or “cell eating, ‘’ the cell engulfs debris, bacteria, or other sizable objects. Phagocytosis occurs in specialized cells called phagocytes, which include macrophages, neutrophils, and other white blood cells.