IMMUNOLOGY

Detailed explanation-1: -Humoral immunity is the aspect of immunity that is mediated by macromolecules-including secreted antibodies, complement proteins, and certain antimicrobial peptides-located in extracellular fluids. Humoral immunity is named so because it involves substances found in the humors, or body fluids.

Detailed explanation-2: -Humoral immunity is the process of adaptive immunity manifested by the production of antibodies by B lymphocytes. It develops in bone marrow. B cells may be triggered to proliferate into plasma cells. Plasma cells produce antibodies.

Detailed explanation-3: -Humoral immunity is also called antibody-mediated immunity. With assistance from helper T cells, B cells will differentiate into plasma B cells that can produce antibodies against a specific antigen. The humoral immune system deals with antigens from pathogens that are freely circulating, or outside the infected cells.

Detailed explanation-4: -B cells, which mature in the bone marrow, are responsible for antibody-mediated immunity.

Detailed explanation-5: -The major difference between humoral and cell-mediated immunity is that humoral immunity produces antigen-specific antibodies, whereas cell-mediated immunity does not.