IMMUNOLOGY

OVERVIEW OF THE IMMUNE SYSTEM

IMMUNITY INNATE AND ADAPTIVE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Place the steps of first exposure cell mediated immunity in order. cytotoxic T-Cells enter circulation and search for antigen displacying cells, attack and destroy the antigen either directly or indirectly production of more helper T cells, cytotoxic cells, memory T-Cells, and B-Cellsclones of memory T-cells remain in lymphatic tissue and Lymph nodes suppressor T-Cells appear when antigen destroyedhelper T-cells bind to antigen and macrophage and lymphokines releasedAntigen engulfed by marcrophage, ID’ed, and monokines are released
A
1, 2, 3, 4, 5, 6
B
5, 6, 3, 4, 2, 1
C
6, 5, 2, 1, 4, 3
D
4, 1, 3, 6, 2, 5
Explanation: 

Detailed explanation-1: -The adaptive immune response in B cells, Helper T cells and Cytotoxic T cells involved four phases: encounter, activation, attack, and memory. in this response, activated T cells differentiate and proliferate, becoming Helper (TH) cells or Cytotoxic (TC) cells.

Detailed explanation-2: -There are three stages during T cells activation by DCs, namely antigen presenting, antigen recognition of T cells and two signals formation. In addition, IS formation between T cells and DCs plays an important role in T cell activation.

Detailed explanation-3: -There are 3 stages in the process of cell-mediated immunity. These are: Cognitive-It shows foreign antigens in a particular form recognized by helper T (Th1) lymphocytes. Activation-Th1 cells produce cytokines to help in the proliferation & differentiation of all T cells and macrophages.

Detailed explanation-4: -Antigen enters tissues, lymphocytes sensitised, antigen passed to members of a clone of lymphocytes, macrophages engulr antigen, T-lymphocytes attack antigen-bearing agents.

Detailed explanation-5: -The normal immune response can be broken down into four main components: pathogen recognition by cells of the innate immune system, with cytokine release, complement activation and phagocytosis of antigens.

There is 1 question to complete.