IMMUNOLOGY

Detailed explanation-1: -Autoimmune disease occurs when a specific adaptive immune response is mounted against self antigens. The normal consequence of an adaptive immune response against a foreign antigen is the clearance of the antigen from the body.

Detailed explanation-2: -If you have an autoimmune disease, your immune system attacks healthy cells in your body by mistake. Other immune system problems happen when your immune system does not work correctly. These problems include immunodeficiency diseases. If you have an immunodeficiency disease, you get sick more often.

Detailed explanation-3: -Autoimmune Disease Basics Autoimmune disease happens when the body’s natural defense system can’t tell the difference between your own cells and foreign cells, causing the body to mistakenly attack normal cells. There are more than 80 types of autoimmune diseases that affect a wide range of body parts.

Detailed explanation-4: -An autoimmune disorder occurs when the body’s immune system attacks and destroys healthy body tissue by mistake. There are more than 80 types of autoimmune disorders.

Detailed explanation-5: -On a basic level, autoimmune disease occurs because the body’s natural defenses-the immune system-attack the body’s own healthy tissue. Researchers have several ideas about why this happens. When the body senses danger from a virus or infection, the immune system kicks into gear and attacks it.

Detailed explanation-6: -Those T cells with high affinity receptors for MHC plus self-peptides undergo clonal deletion which is also called negative selection through induction of apoptosis. Any disturbance in this process can lead to the escape of auto-reactive T cells that may trigger autoimmune disease.