OVERVIEW OF THE IMMUNE SYSTEM
IMMUNITY INNATE AND ADAPTIVE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Macrophages
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Mast cells
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Neutrophils
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B cells
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Detailed explanation-1: -Mast cells play a critical role in the pathogenesis of allergic asthma. Histamine is a central mediator released from mast cells through allergic reactions.
Detailed explanation-2: -IgE, mast cells, basophils, and eosinophils are essential components of allergic inflammation. Antigen-specific IgE production, with subsequent fixation of IgE to FcRI receptors on mast cells and basophils, is central to the initiation and propagation of immediate hypersensitivity reactions.
Detailed explanation-3: -Histamine is not only released when the body encounters a toxic substance, it is also released when mast cells detect injury. It causes nearby blood vessels to dilate allowing more blood to reach the site of the injury or infection.