IMMUNOLOGY

Detailed explanation-1: -Self-tolerance is the ability of the immune system to recognize self-produced antigens as a non-threat while appropriately mounting a response to foreign substances. This balance of immunological defense and self-tolerance is critical to normal physiological function and overall health.

Detailed explanation-2: -Tolerance is the prevention of an immune response against a particular antigen. For instance, the immune system is generally tolerant of self-antigens, so it does not usually attack the body’s own cells, tissues, and organs.

Detailed explanation-3: -What Is Tolerance in Immunology? Immune tolerance, or immunological tolerance, is the process by which immune cells are made unresponsive to self-antigens to prevent damage to healthy tissues. It prevents an immune response to antigens produced by the body itself or recognized from a prior encounter.

Detailed explanation-4: -The immune response is how your body recognizes and defends itself against bacteria, viruses, and substances that appear foreign and harmful.

Detailed explanation-5: -This ability to differentiate self (the body’s own normal cells) from nonself (abnormal/foreign cells) is a hallmark of the immune response. The capacity of the immune system to recognize self-antigens and accept the presence of normal cells is known as self-tolerance.

Detailed explanation-6: -Immune tolerance is a state in which the immune system is specifically unresponsive to antigens of interest. For example, most people enjoy a state of immune tolerance to their own antigens, resulting in freedom from autoimmune disease.