IMMUNOLOGY

Detailed explanation-1: -Vaccines contain weakened or inactive parts of a particular organism (antigen) that triggers an immune response within the body. Newer vaccines contain the blueprint for producing antigens rather than the antigen itself.

Detailed explanation-2: -An antigen specifically induces the production of antibodies which can bind to it and neutralise it. While most vaccines work by inducing B lymphocytes to produce antibodies (see below), activation of T-cells-another type of immune system cell that helps protect against disease-is also important for some vaccines.

Detailed explanation-3: -For example, in response to an infection or vaccination with a live virus, IgM antibodies usually are made first, followed by IgG and some other types of antibodies. For the most part, the antibodies that you form from getting vaccinated are the same kind of antibodies you would get from a natural infection.

Detailed explanation-4: -Vaccines provide active immunity to disease. Vaccines do not make you sick, but they can trick your body into believing it has a disease, so it can fight the disease.

Detailed explanation-5: -When you get a vaccine, it sparks your immune response, helping your body fight off and remember the germ so it can attack it if the germ ever invades again. And since vaccines are made of very small amounts of weak or dead germs, they won’t make you sick.

Detailed explanation-6: -The immune response to a pure polysaccharide vaccine is typically T-cell-independent, which means these vaccines can stimulate B-cells without the assistance of T-helper cells.

Detailed explanation-7: -The immune system has special cells (known as B cells) that make the antibodies. It takes time for your body’s immune system to recognise the pathogens that can make you ill. This could take a week, or sometimes as long as 3 weeks.