IMMUNOLOGY

OVERVIEW OF THE IMMUNE SYSTEM

IMMUNITY INNATE AND ADAPTIVE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is the role of antibodies in the immune system?
A
To actively destroy pathogens
B
To mark pathogens that need to be destroyed by T-cells
C
To safeguard the body against being destroyed by its own immune system
D
To bind to B-cells, helping them in their support of T-cells
Explanation: 

Detailed explanation-1: -Antibodies help the body to fight microbes or the toxins (poisons) they produce. They do this by recognising substances called antigens on the surface of the microbe, or in the chemicals they produce, which mark the microbe or toxin as being foreign. The antibodies then mark these antigens for destruction.

Detailed explanation-2: -A unique function of antibody is to initiate the clearance of pathogens via complement activation and binding to erythrocyte complement receptor 1 (CR1); the result of such binding sequesters the pathogen from invading susceptible tissue and may facilitate the destruction of the organisms by tissue macrophages (112).

Detailed explanation-3: -Antibodies are proteins produced by the immune system in response to infection. They are an important part of the body’s defence system as they work to destroy disease-causing organisms (such as viruses or bacteria) and block them from infecting human cells.

Detailed explanation-4: -An antibody’s function in the immune system is to specifically bind and eliminate foreign particles. Antibodies may remove foreign antigens through several mechanisms. Neutralization-Antibody binding serves to neutralize foreign particles preventing interaction with cells and consequent cellular damage and invasion.

Detailed explanation-5: -Antibodies help stop pathogens from infecting the host in one of three ways: opsonization, agglutination, and neutralization. During opsonization, antibodies bind with antigens to form an antigen-antibody complex.

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