IMMUNOLOGY

Detailed explanation-1: -Hemophilia is usually an inherited bleeding disorder in which the blood does not clot properly. This can lead to spontaneous bleeding as well as bleeding following injuries or surgery. Blood contains many proteins called clotting factors that can help to stop bleeding.

Detailed explanation-2: -Due to a lack of these protein factors, a hemophilic person is unable to complete the cascade of clotting reactions and is associated with bleeder’s disease. Hence, it is called bleeder’s disease as it leads to cessation in clotting and can lead to spontaneous bleeding if injured.

Detailed explanation-3: -Definitions of bleeder’s disease. congenital tendency to uncontrolled bleeding; usually affects males and is transmitted from mother to son. synonyms: haemophilia, hemophilia.

Detailed explanation-4: -Some bleeding disorders are present at birth and are passed down through families (inherited). Others develop from: Illnesses, such as vitamin K deficiency or severe liver disease. Treatments, such as the use of drugs to stop blood clots (anticoagulants) or the long-term use of antibiotics.

Detailed explanation-5: -What is von Willebrand Disease? Von Willebrand disease (VWD) is an inheritable bleeding disorder. Many different proteins are needed to make a person’s blood clot successfully. People with VWD are either missing or low in the clotting protein von Willebrand factor (VWF) – or it doesn’t work as it’s supposed to.