IMMUNOLOGY

OVERVIEW OF THE IMMUNE SYSTEM

LYMPHATIC AND IMMUNE SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Chemical substance produced by certain cells that initiates, inhibits, increases, or decreases activity in other cells
A
Sytokine
B
Cytocine
C
Cytokine
D
Sytokine
Explanation: 

Detailed explanation-1: -It is known that TGF- suppresses cytokine production by inhibiting macrophage and Th1 cell activity; counteracts IL-1, IL-2, IL-6, and TNF; and induces IL-1ra 6 [34].

Detailed explanation-2: -The damaged cells release chemicals including histamine, bradykinin, and prostaglandins. These chemicals cause blood vessels to leak fluid into the tissues, causing swelling.

Detailed explanation-3: -Mast cells, which are important innate immune cells in allergy and inflammatory diseases that reside in tissues, secrete numerous cytokines and chemokines, many of which are stored as preformed mediators in their secretory granules.

Detailed explanation-4: -The cytokine IL-21 has been shown to play a major role in antibody production by promoting the differentiation of B cells into plasma cells both in mice and humans (16, 17). Accordingly, IL-21 promotes the production of IgG1, IgG2a, and IgG3, but it has an inhibitory effect on IgE production (18).

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