IMMUNOLOGY

Detailed explanation-1: -In summary, agglutination is the clumping together of cells. Agglutination of red blood cells is called hemagglutination, whereas the agglutination of white blood cells is called leukoagglutination.

Detailed explanation-2: -Agglutination, which refers to the clumping of particles together, is an antigen-antibody reaction that occurs when an antigen (i.e., a molecule capable of triggering the adaptive immune response) is mixed with its corresponding antibody at a suitable pH and temperature.

Detailed explanation-3: -Agglutination is defined as the formation of clumps of cells or inert particles by specific antibodies to surface antigenic components (direct agglutination) or to antigenic components adsorbed or chemically coupled to red cells or inert particles (passive hemagglutination and passive agglutination, respectively).

Detailed explanation-4: -Clumping (agglutination) of red blood cells is frequently caused by cold agglutinins. Cold agglutinins are IgM antibodies that may arise following viral or Mycoplasma infections, or in the setting of plasma cell or lymphoid neoplasms. Agglutination of red cells can interfere with red blood cell indices.