OVERVIEW OF THE IMMUNE SYSTEM
LYMPHATIC AND IMMUNE SYSTEM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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are chemotactic
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stimulate RBC production
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decrease B cell activity
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decrease leukopoiesis
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Detailed explanation-1: -Recent interest has centered on the chemokine family of cytokines, different members of which are specific attractants for particular leukocytes, and which are believed to play a central role in inflammation.
Detailed explanation-2: -Introduction. The attraction of leukocytes to tissues is essential for inflammation and the host response to infection. The process is controlled by chemokines, which are chemotactic cytokines.
Detailed explanation-3: -Fibrinopeptide B, a fibrin degradation product and Kallikrein, a clotting cascade enzyme, both have chemotactic activity.
Detailed explanation-4: -Definition. Chemotactic factors are substances that stimulate cellular locomotion/migration1. Some examples include formyl peptides, chemokines and complement proteins-3a and 5a1. Discovery. Chemotaxis and chemotactic factors were described as early as 1880’s.
Detailed explanation-5: -Chemotactic cytokines and inflammation. Biological properties of the lymphocyte and monocyte chemotactic factors ELCF, MCAF and IL-8.