IMMUNOLOGY

OVERVIEW OF THE IMMUNE SYSTEM

LYMPHATIC AND IMMUNE SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
How does the HIV virus attack?
A
it kills the antibodies in your body
B
it prevents you from making new antibodies
C
it prevents your body from remembering the diseases you have already had
D
it attacks WBCs so your body can’t fight infection
Explanation: 

Detailed explanation-1: -White blood cells are an important part of the immune system. HIV infects and destroys certain white blood cells called CD4+ cells. If too many CD4+ cells are destroyed, the body can no longer defend itself against infection. The last stage of HIV infection is AIDS (acquired immunodeficiency syndrome).

Detailed explanation-2: -HIV finds the white blood cells, called CD4 cells. HIV gets inside the CD4 cell and makes copies of itself. Then, HIV kills the CD4 cell and the new HIV copies find other CD4 cells to get inside and start the cycle again. HIV kills immune system cells that help the body fight infections and diseases.

Detailed explanation-3: -To infect cells, the HIV protein envelope (Env) binds to the primary cellular receptor CD4 and then to a cellular coreceptor. This sequential binding triggers fusion of the viral and host cell membranes, initiating infection.

Detailed explanation-4: -HIV causes your body to produce more CD4 cells to fight this new infection. These new cells provide more cells for HIV to infect and reproduce. The body responds by making even more cells to fight the new virus etc. This cycle continues every day and slowly, usually over many years, the immune system becomes worn out.

Detailed explanation-5: -Taking antiretroviral therapy regularly helps many people slow the progression of HIV and reach viral suppression. However, a variety of factors affect HIV progression, and some people progress through the phases of HIV more quickly than others.

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