IMMUNOLOGY

Detailed explanation-1: -Immunodeficiency disorders may affect any part of the immune system. Most often, these conditions occur when special white blood cells called T or B lymphocytes (or both) do not function normally or your body does not produce enough antibodies.

Detailed explanation-2: -A person with a weak immune system may be more prone to frequent infections. White blood cells, antibodies, and other components, including organs and lymph nodes, make up the body’s immune system. Many disorders can weaken the immune system and cause a person to become immunocompromised.

Detailed explanation-3: -Wiskott-Aldrich Syndrome (WAS) The disorder is characterized by abnormal immune function and a reduced ability to form blood clots. This can result in prolonged episodes of bleeding, recurrent bacterial and fungal infections, and increased risk of cancers and autoimmune diseases.

Detailed explanation-4: -Immunodeficiency, also known as immunocompromisation, is a state in which the immune system’s ability to fight infectious diseases and cancer is compromised or entirely absent. Most cases are acquired ("secondary") due to extrinsic factors that affect the patient’s immune system.

Detailed explanation-5: -Worldwide, the most common causes are HIV, malnutrition, and unsanitary conditions.

Detailed explanation-6: -Common Variable Immune Deficiency (CVID) is one of the most frequently diagnosed primary immunodeficiencies, especially in adults, characterized by low levels of serum immunoglobulins and antibodies, which causes an increased susceptibility to infection.

Detailed explanation-7: -Primary immunodeficiency disorders-also called primary immune disorders or primary immunodeficiency-weaken the immune system, allowing infections and other health problems to occur more easily.