IMMUNOLOGY

OVERVIEW OF THE IMMUNE SYSTEM

LYMPHATIC AND IMMUNE SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Vaccines train cells to recognize pathogens in the future. Which cells are we trying to produce with vaccination?
A
memory B-cells
B
plasma B-cells
C
cytotoxic T-cells
D
helper T-cells
Explanation: 

Detailed explanation-1: -B cells secrete antibodies and mediate the humoral immune response, making them extremely important in protective immunity against SARS-CoV-2, which caused the coronavirus disease 2019 (COVID-19) pandemic.

Detailed explanation-2: -After immunization, dendritic cells take up microbial antigens and traffic to draining lymph nodes where they present processed antigens to naïve T cells. These naïve T cells are stimulated to proliferate and differentiate into effector and memory T cells.

Detailed explanation-3: -2 Memory B cell response. Although existing antibodies in mucosal tissues can prevent humans from pathogen infections like COVID-19, MBCs play an important role during reinfection by responding locally to increase production of antigen-specific antibodies in a short period of time.

Detailed explanation-4: -Live-attenuated vaccines contain live pathogens from either a bacteria or a virus that have been “attenuated, ‘’ or weakened. According to Dr. Scully, live-attenuated vaccines are produced by selecting strains of a bacteria or virus that still produce a robust enough immune response but that does not cause disease.

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