IMMUNOLOGY

Detailed explanation-1: -Systemic inflammation-associated syndromes (e.g., sepsis and septic shock) often have high mortality and remain a challenge in emergency medicine. Systemic inflammation is usually accompanied by changes in body temperature: fever or hypothermia.

Detailed explanation-2: -Systemic autoinflammatory diseases (SAIDs), sometimes called periodic fever syndromes, are a group of conditions that result from an inappropriate inflammatory response by the body. In general, these conditions cause recurrent episodes of unexplained fever and inflammation.

Detailed explanation-3: -Fever is a hallmark of infectious and inflammatory diseases. It is generated by the concerted action of various autonomic responses, such as peripheral vasoconstriction and decreased sweating, reducing heat loss, and shivering, and possibly also non-shivering, thermogenesis.

Detailed explanation-4: -Systemic inflammation can lead to immune responses in the brain that show up in many ways. People may experience cognitive symptoms such as memory lapses or confusion. Other common symptoms, known as “sickness behavior, ‘’ may include: Depression. Decreased physical activity.

Detailed explanation-5: -Fever. Painful and tender joints-most often in the knees, ankles, elbows and wrists. Pain in one joint that migrates to another joint. Red, hot or swollen joints. Chest pain. Fatigue. Flat or slightly raised, painless rash with a ragged edge. Heart murmur. More items •19-Apr-2022