IMMUNOLOGY

Detailed explanation-1: -NK cells can induce apoptotic or necrotic cell death in their respective targets and potentially also induce “mixed” forms of target cell death.

Detailed explanation-2: -Natural killer (NK) cells are lymphocytes of the innate immune system that participate in early defense against foreign cells and autologous cells undergoing various forms of stress, such as microbial infection or tumour transformation [1, 2].

Detailed explanation-3: -There are two main types of T-cells: Helper T-cells stimulate B-cells to make antibodies and help killer cells develop. Killer T-cells or cytotoxic T-cells directly kill cells that have already been infected by a foreign invader.

Detailed explanation-4: -Natural killer (NK) cells target and kill aberrant cells, such as virally infected and tumorigenic cells. Killing is mediated by cytotoxic molecules which are stored within secretory lysosomes, a specialized exocytic organelle found in NK cells.