IMMUNOLOGY

Detailed explanation-1: -An organ that is part of the lymphatic system. The spleen makes lymphocytes, filters the blood, stores blood cells, and destroys old blood cells.

Detailed explanation-2: -Your spleen’s main function is to act as a filter for your blood. It recognizes and removes old, malformed, or damaged red blood cells. When blood flows into your spleen, your spleen performs “quality control"; your red blood cells must pass through a maze of narrow passages.

Detailed explanation-3: -The spleen filters blood in much the way that the lymph nodes filter lymph. Lymphocytes in the spleen react to pathogens in the blood and attempt to destroy them. Macrophages then engulf the resulting debris, the damaged cells, and the other large particles.

Detailed explanation-4: -Spleen. The spleen is located in the abdominal (tummy) area on the left side, just under the diaphragm. It is the largest of our lymphatic organs. The spleen does many things as it filters and monitors our blood.

Detailed explanation-5: -The spleen also removes unhealthy, old, and misshapen red blood cells from circulation. Red blood cells carry oxygen throughout the body and remove carbon dioxide (a waste product). These disc-shaped cells are filtered by the spleen based on their physical characteristics.

Detailed explanation-6: -The red pulp is a network of splenic cords (cords of Billroth) and sinusoids (wide vessels) filled with blood, and it is in the red pulp that most of the filtration occurs.

Detailed explanation-7: -Modeling blood filtration As blood flows through the spleen, about 10 percent of the red blood cells are diverted through these slits, which have maximum dimensions of 1.2 micrometers in height (about 1/80 the thickness of a human hair), 4 micrometers in width, and 1.9 micrometers in depth.