IMMUNOLOGY

Detailed explanation-1: -Always economical, your spleen saves any useful components from the old cells, such as iron. It stores iron in the form of ferritin or bilirubin, and eventually returns the iron to your bone marrow, where hemoglobin is made.

Detailed explanation-2: -The human body stores iron in the form of ferritin and hemosiderin in liver, spleen, marrow, duodenum, skeletal muscle and other anatomic areas.

Detailed explanation-3: -The liver is a major storage organ of iron, in which excess iron is stored as ferritin and hemosiderin. In addition to these proteins, an additional fraction of free iron is present in the form of the labile iron pool (LIP) within cells.

Detailed explanation-4: -Macrophages in the red pulp of the spleen destroy senescent red blood cells and recycle the stored iron to be further incorporated into maturating RBCs during erythropoiesis.