IMMUNOLOGY

Detailed explanation-1: -It usually happens in the arms or legs, but can occur in other parts of the body. Lymph fluid is part of the lymph system that carries fluid and cells that help fight infections throughout the body. Sometimes this swelling develops quickly, or it may develop slowly over several months.

Detailed explanation-2: -Lymphedema can cause swelling of a toe or toes all the way to extreme swelling of one or both legs. Symptoms also include restricted movement and feeling heavy or tight along the whole leg. There can be leg pain and aching. There can also be fibrosis, or hardening and thickening of the skin.