IMMUNOLOGY

Detailed explanation-1: -In the lymphatic system a lymph node is a secondary lymphoid organ. A lymph node is enclosed in a fibrous capsule and is made up of an outer cortex and an inner medulla.

Detailed explanation-2: -The outer cortex has lymphatic nodules that mostly contain B-cells.

Detailed explanation-3: -The medulla is the innermost layer of the lymph node and contains large blood vessels, sinuses, and medullary cords. The medullary cords contain antibody-secreting plasma cells, B-cells, and macrophages.

Detailed explanation-4: -The cortex is mainly composed of clusters of B cells in the outer layers and T cells in the inner layers, and may also contain antigen-presenting dendritic cells. The medulla contains plasma cells, macrophages, and B cells as well as sinuses, which are vessel-like spaces that the lymph flows into.