OVERVIEW OF THE IMMUNE SYSTEM
LYMPHOCYTE SUBPOPULATION IN HUMANS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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CD8+ T-cells
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CD2+ T-cells
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CD4+ T-cells
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CD3+ T-cells
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Detailed explanation-1: -Armed effector cytotoxic CD8 T cells are essential in host defense against pathogens that live in the cytosol, the commonest of which are viruses. These cytotoxic T cells can kill any cell harboring such pathogens by recognizing foreign peptides that are transported to the cell surface bound to MHC class I molecules.
Detailed explanation-2: -CD8+ T cells (often called cytotoxic T lymphocytes, or CTLs) are very important for immune defence against intracellular pathogens, including viruses and bacteria, and for tumour surveillance.
Detailed explanation-3: -A cytotoxic T cell is a type of white blood cell and a type of lymphocyte. Also called cytotoxic T lymphocyte and killer T cell.
Detailed explanation-4: -CD4 T cells are MHC-II restricted and pre-programmed for helper functions, whereas CD8 T cells are MHC I-restricted and pre-programmed for cytotoxic functions. CD4 and CD8 subsets constitute the bulk of T cells and are the main component of T-mediated immune responses.