OVERVIEW OF THE IMMUNE SYSTEM
LYMPHOCYTE SUBPOPULATION IN HUMANS
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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To activate B cell
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To activate Plasma cell
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To activate Helper T cell
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To activate
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Detailed explanation-1: -IL-2 has an immunoregulatory role; it promotes the growth and development of peripheral immune cells in the initiation of the (defensive) immune response, and keeps them alive as effector cells.
Detailed explanation-2: -TH cells activate B cells by their products, cytokines such as IL-4, IL-5, and IL-6, and membrane-bound stimulatory molecules including CD40 ligand. Each cytokine has pleiotropic activity on B cells and other cell types, and acts through a specific receptor.
Detailed explanation-3: -IL-2 was found to stimulate B cell proliferation. Activation of the B cells using anti-IgM antibodies increased this response. Resting T cells from the same donors were found to be less reactive to IL-2. The results suggest that human B cell proliferation can be stimulated by IL-2 alone.