IMMUNOLOGY

Detailed explanation-1: -A chemotherapy regimen consisting of doxorubicin, bleomycin, vinblastine and dacarbazine, used alone or in combination with radiation therapy, for the primary treatment of Hodgkin lymphoma.

Detailed explanation-2: -Thus, vinblastine is currently used in the treatment of Hodgkin’s disease and metastatic testicular tumors, for which it is combined with bleomycin and cisplatin, whereas vincristine is used in the treatment of leukemia and lymphomas. Several semisynthetic analogs of these alkaloids9 are also in clinical use.

Detailed explanation-3: -Drugs used in the chemotherapy, such as doxorubicin, vinblastine, dacarbazine, and brentuximab vedotin, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, and/or by stopping them from spreading.