OVERVIEW OF THE IMMUNE SYSTEM
ONTOGENY AND PHYSIOLOGY OF IMMUNE SYSTEM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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part of the interferons that penetrate foreign cells.
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a protein protruding from the surface of B cells.
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two structurally similar antibodies dissolved in the blood plasma
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that part of an antigen that actually binds to an antigen receptor.
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Detailed explanation-1: -An epitope is the part of the antigen that binds to a specific antigen receptor on the surface of a B cell. Binding between the receptor and epitope occurs only if their structures are complementary.
Detailed explanation-2: -The small site on an antigen to which a complementary antibody may specifically bind is called an epitope or antigenic determinant. This is usually one to six monosaccharides or five to eight amino acid residues on the surface of the antigen.
Detailed explanation-3: -The epitope An epitope is the part of an antigen that the host’s immune system recognizes, eliciting the immune response to an invading pathogen.
Detailed explanation-4: -In immunology, a paratope, also known as an antigen-binding site, is the part of an antibody which recognizes and binds to an antigen. It is a small region at the tip of the antibody’s antigen-binding fragment and contains parts of the antibody’s heavy and light chains.
Detailed explanation-5: -The immunoglobulin recognizes and binds antigen but cannot itself generate a signal.
Detailed explanation-6: -When the VH and VL domains are paired in the antibody molecule, the hypervariable loops from each domain are brought together, creating a single hypervariable site at the tip of each arm of the molecule. This is the binding site for antigen, the antigen-binding site or antibody combining site.
Detailed explanation-7: -An epitope is the part of an antigen that interacts with both constant and variable regions of light and heavy chains of the antigen receptors.