IMMUNOLOGY

OVERVIEW OF THE IMMUNE SYSTEM

THE GOOD BAD AND UGLY OF THE IMMUNE SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
After an initial infection, B-cells recognize the measles virus. How is this helpful in human immune response?
A
The B-cells use this recognition to defend the body against other pathogens, such as bacteria.
B
The B-cells more quickly recognize and respond to any other virus that invades the body.
C
The B-cells produce antibodies more quickly if the measles virus is encountered again.
D
The B-cells transfer this recognition to T-cells, which will then devour the viruses.
Explanation: 

Detailed explanation-1: -After an initial infection, B-cells recognize the measles virus. How is this helpful in human immune response? A. The B-cells use this recognition to defend the body against other pathogens, such as bacteria.

Detailed explanation-2: -B cells create antibodies. These antibodies bind to pathogens or to foreign substances, such as toxins, to neutralize them. For example, an antibody can bind to a virus, which prevents it from entering a normal cell and causing infection. B cells can also recruit other cells to help destroy an infected cell.

Detailed explanation-3: -Measles has a complex interaction with the immune system through direct infection of B and T lymphocytes expressing CD150 that results in transient lymphocyte depletion followed by immune activation that generates life-long immunity to reinfection.

Detailed explanation-4: -Immunity to a disease is achieved through the presence of antibodies to that disease in a person’s system. Antibodies are proteins produced by the body to neutralize or destroy toxins or disease-carrying organisms. Antibodies are disease-specific.

Detailed explanation-5: -The immune system response to a virus. (1) Virus bearing an antigenic epitope. (2) Processing of antigen to fragments. (3) Presentation of antigen (Ag) to T cells (on the infected cell surface) and B cells (free antigenic pieces or viruses).

Detailed explanation-6: -B cells secrete antibodies and mediate the humoral immune response, making them extremely important in protective immunity against SARS-CoV-2, which caused the coronavirus disease 2019 (COVID-19) pandemic.

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