IMMUNOLOGY

OVERVIEW OF THE IMMUNE SYSTEM

THE GOOD BAD AND UGLY OF THE IMMUNE SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What can happen to a pathogen that has antibodies attached to its surface?
A
it is identified by macrophage
B
the kidney filters it out
C
B cells consume it
D
T cells blow it up
Explanation: 

Detailed explanation-1: -The antibodies destroy the antigen (pathogen) which is then engulfed and digested by macrophages.

Detailed explanation-2: -Macrophages detect pathogenic microorganisms by expressing pattern recognition receptors (PRRs), which interact with conserved microbe-associated molecular patterns (MAMPs).

Detailed explanation-3: -The secreted antibodies bind to antigens on the surface of pathogens, flagging them for destruction through complement activation, opsonin promotion of phagocytosis and pathogen elimination by immune effector cells.

Detailed explanation-4: -Agglutination describes how pathogens carrying antigen–antibody complexes clump together. Forming clumps prevents the pathogens from spreading through the body so easily. This also makes it easier for phagocytes to engulf several pathogens at once.

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