IMMUNOLOGY

OVERVIEW OF THE IMMUNE SYSTEM

THE GOOD BAD AND UGLY OF THE IMMUNE SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Where do T cells mature?
A
lymph node
B
bone marrow
C
thymus
D
liver
Explanation: 

Detailed explanation-1: -In the case of T cells, development is compartmentalized, with different types of stromal cells in the thymic cortex and medulla. Most steps in T-cell differentiation occur in the cortex of the thymus. The thymic medulla contains mainly mature T cells.

Detailed explanation-2: -Bone marrow: T-cells start in the spongy tissue inside your bone called marrow. Like all blood cells, they start as hematopoietic stem cells. These cells have the potential to develop into any type of blood cell. Thymus: T-cells move to an organ called your thymus (located in your upper mid-chest) to mature.

Detailed explanation-3: -The thymus supports the differentiation of multiple distinct T cell subsets that play unique roles in the immune system. CD4 and CD8 / T cells, / T cells, NKT cells, Treg, and IEL all develop in and must leave the thymus to provide their functions elsewhere in the body.

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