IMMUNOLOGY

Detailed explanation-1: -IgM is the primary antibody produced during an initial antigen challenge. Yet, upon subsequent antigen exposure, follicular B cells undergo isotype switching, resulting in IgG, IgG, IgE, or IgA production.

Detailed explanation-2: -IgM is the first antibody produced in primary immune response.

Detailed explanation-3: -Primary Immune Response: A large amount of IgM and a small amount of IgG are produced during the primary immune response. Secondary Immune Response: A large amount of IgG, a small amount of IgM, IgA, and IgE are produced during the secondary immune response.

Detailed explanation-4: -IgM is the first antibody isotype produced during an immune response and functions as a primary barrier against pathogens. IgM also regulates immune responses. Thus, antigen-specific IgM administered before immunization enhances antibody response, which depends on complement (1).

Detailed explanation-5: -The secondary antibody response is characterized in its first few days by the production of small amounts of IgM antibody and larger amounts of IgG antibody, with some IgA and IgE.

Detailed explanation-6: -5 types of antibodies, each with a different function IgG is the main antibody in blood and it has a powerful ability to bind to bacteria and toxins, and thus it takes on an important role in the biological defense system.