IMMUNOLOGY

Detailed explanation-1: -The extracellular spaces are protected by the humoral immune response, in which antibodies produced by B cells cause the destruction of extracellular microorganisms and prevent the spread of intracellular infections. The activation of B cells and their differentiation into antibody-secreting plasma cells (Fig.

Detailed explanation-2: -B cells. B cells (sometimes called B-lymphocytes and often named on lab reports as CD19 or CD20 cells) are specialized cells of the immune system whose major function is to produce antibodies (also known as immunoglobulins or gamma-globulins). B cells develop in the bone marrow from stem cells.

Detailed explanation-3: -Humoral immunity is also called antibody-mediated immunity. With assistance from helper T cells, B cells will differentiate into plasma B cells that can produce antibodies against a specific antigen. The humoral immune system deals with antigens from pathogens that are freely circulating, or outside the infected cells.

Detailed explanation-4: -Humoral immunity is the process of adaptive immunity manifested by the production of antibodies by B lymphocytes. It develops in bone marrow. B cells may be triggered to proliferate into plasma cells. Plasma cells produce antibodies.

Detailed explanation-5: -The major difference between humoral and cell-mediated immunity is that humoral immunity produces antigen-specific antibodies, whereas cell-mediated immunity does not.