MICROANATOMY

BLOOD CARDIOVASCULAR SYSTEM LYMPHOID ORGANS

LYMPH NODES

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following is a nonspecific defense protein that inhibits bacterial growth by limiting iron?
A
interferons
B
transferrin
C
phagocytes
D
natural killer cells
Explanation: 

Detailed explanation-1: -Mammals employ iron-binding proteins (transferrin, lactoferrin) to reduce the levels of free extracellular iron to around 10−18 M [62], levels insufficient to allow bacterial growth [63].

Detailed explanation-2: -Given the absolute requirement for iron by virtually all human pathogens, an important facet of the innate immune system is to limit iron availability to invading microbes in a process termed nutritional immunity.

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