BLOOD CARDIOVASCULAR SYSTEM LYMPHOID ORGANS
LYMPH NODES
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which of the following is a nonspecific defense protein that inhibits bacterial growth by limiting iron?
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interferons
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transferrin
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phagocytes
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natural killer cells
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Explanation:
Detailed explanation-1: -Mammals employ iron-binding proteins (transferrin, lactoferrin) to reduce the levels of free extracellular iron to around 10−18 M [62], levels insufficient to allow bacterial growth [63].
Detailed explanation-2: -Given the absolute requirement for iron by virtually all human pathogens, an important facet of the innate immune system is to limit iron availability to invading microbes in a process termed nutritional immunity.
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