MICROANATOMY

Detailed explanation-1: -The human pancreas secretes an impressive amount of sodium-bicarbonate–rich fluid with each meal. The majority of fluid and bicarbonate in pancreatic juice arises from the pancreatic duct cells, although they comprise only 5% of the pancreatic mass.

Detailed explanation-2: -Epithelial cells in pancreatic ducts are the source of the bicarbonate and water secreted by the pancreas. Bicarbonate is a base and critical to neutralizing the acid coming into the small intestine from the stomach.

Detailed explanation-3: -Ductal cells of the pancreas form the epithelial lining of the branched tubes that deliver enzymes produced by pancreatic acinar cells into the duodenum. In addition, these cells secrete bicarbonate that neutralizes stomach acidity.