MICROANATOMY

Detailed explanation-1: -Parathyroid glands play a key role in maintaining the extracellular calcium concentration. The parathyroid gland is composed of two types of cells: chief and the oxyphil. Parathyroid chief cells, the main type of parathyroid gland cells, produce PTH. Oxyphil cells produce PTHrP, calcitriol, and some other factors.

Detailed explanation-2: -The chief cells are the functional cells of the parathyroid gland, responsible for both synthesizing and secreting parathyroid hormone. Regulation of PTH production and release is dependent on serum calcium levels.

Detailed explanation-3: -Oxyphil cells of the thyroid are cytochemically akin to C cells but arise from follicular cells. They occur in the thyroid and other protein-producing organs, but are themselves inefficient producers of proteins and glycoproteins.

Detailed explanation-4: -Oxyphil cells, also known as oncocytes, are found in oncocytomas of the kidney, salivary glands, and endocrine glands. In the thyroid gland, oxyphil cells are known as Hurthle cells and Askenazy cells.