MICROANATOMY

Detailed explanation-1: -Regulation of thyroid hormone starts at the hypothalamus. The hypothalamus releases thyrotropin-releasing hormone (TRH) into the hypothalamic-hypophyseal portal system to the anterior pituitary gland. TRH stimulates thyrotropin cells in the anterior pituitary to the release of thyroid-stimulating hormone (TSH).

Detailed explanation-2: -Thyroxine (T4) is produced by the thyroid gland under regulation from the hypothalamus and pituitary gland. The feedback loop signals to the hypothalamus in to release thyrotropin-releasing hormone, which then stimulates the pituitary gland to release the thyroid stimulating hormone.

Detailed explanation-3: -The pituitary is an endocrine gland located at the base of your brain that controls your endocrine system, including your thyroid. The pituitary affects the thyroid by producing a hormone called thyroid stimulating hormone (TSH).