MICROANATOMY

Detailed explanation-1: -Prealbumin. Prealbumin, also known as thyroxine-binding prealbumin, or transthyretin, is a sensitive marker for assessing the severity of illness in children who have critical or chronic disease, and correlates with outcomes and recovery.

Detailed explanation-2: -TTR, formerly known as thyroxine-binding prealbumin, is a 55 kDa, highly acidic tetramer devoid of carbohydrate. It forms a complex with retinol-binding protein (RBP) and thus plays a role in the transport of vitamin A.

Detailed explanation-3: -TTR was originally called prealbumin (or thyroxine-binding prealbumin) because it migrated faster than albumin on electrophoresis gels. Prealbumin was felt to be a misleading name, it is not a synthetic precursor of albumin. The alternative name TTR was proposed by DeWitt Goodman in 1981.