MICROANATOMY

Detailed explanation-1: -Osteoblasts are cells responsible for the secretion and deposition of bone morphogenetic proteins (BMPs) into the extracellular matrix during bone formation.

Detailed explanation-2: -Osteoblasts are bone-forming cells that are of mesenchymal origin. They synthesize bone matrix and produce an environment that promotes bone mineralization. Osteocytes are osteoblasts that have become entrapped in bone. Osteoclasts are large, multinucleate cells derived from hematopoietic stem cells.

Detailed explanation-3: -The pericellular matrix (PCM) surrounds the osteocyte and separates the cell from the walls of the lacunae and canaliculi. This matrix contains proteoglycans and hyaluronic acid and may amplify the impacts of mechanical loading to allow osteocyte to sense more load than what would be calculated by tissue strain alone.

Detailed explanation-4: -Osteons are cylindrical structures that contain a mineral matrix and living osteocytes connected by canaliculi, which transport blood. They are aligned parallel to the long axis of the bone. Each osteon consists of lamellae, which are layers of compact matrix that surround a central canal called the Haversian canal.