INTRODUCTION TO MICROSCOPY CELL BIOLOGY
CYTOSKELETON
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Cadherin proteins:
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create an electrical and metabolic coupling between epithelial cells
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link epithelial cells together by binding to similar cadherins in adjacent epithelial cells.
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allow ions and small molecules to pass from one plant cell to another.
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anchor epithelial cells to the basal lamina.
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Explanation:
Detailed explanation-1: -Most cadherins adhere by homophilic interactions (i.e. they bind to the same type of cadherin) but certain types (e.g. E-cadherin) also adhere by heterophilic interactions (i.e. they bind other types of cadherin). Cadherin association is sensitive to extracellular calcium (hence their name, calcium adhering).
Detailed explanation-2: -Intracellular domains of cadherins are also highly conserved, as they bind to proteins called catenins, forming catenin-cadherin complexes. These protein complexes link cadherins to actin filaments. This association with actin filaments is essential for adherens junctions to stabilise cell–cell adhesion.
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