MICROANATOMY

INTRODUCTION TO MICROSCOPY CELL BIOLOGY

CYTOSKELETON

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What of the following is mismatch with tight junctions?
A
forming continuous seals around the cells.
B
prevent leakage of extracellular fluid.
C
small molecules and ions pass through.
D
connect epithelial cells.
Explanation: 

Detailed explanation-1: -Tight junctions: Transmembrane proteins called claudins join the plasma membranes of two cells to create a barrier that limits diffusion of ions and solutes between the cells and molecules between apical and basolateral domains of the plasma membrane.

Detailed explanation-2: -Tight junctions create a watertight seal that does not allow molecules and ions to pass around the connected cells and it forces the molecules to pass through the cell membrane on the apical end (luman side) and out of the cell membrane on the basolateral end (extracellular side).

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