MICROANATOMY

Detailed explanation-1: -Animal cell cleavage furrow formation is caused by a ring of actin microfilaments called the contractile ring, which forms during early anaphase. Myosin is present in the region of the contractile ring as concentrated microfilaments and actin filaments are predominant in this region.

Detailed explanation-2: -In association with myosin, microfilaments help to generate the forces used in cellular contraction and basic cell movements. The filaments also enable a dividing cell to pinch off into two cells and are involved in amoeboid movements of certain types of cells.

Detailed explanation-3: -To complete the cell cycle, the cleavage furrow draws the plasma membrane toward the cell center, pinching the cytoplasm into two lobes that are subsequently separated into two cells. The position of the cleavage furrow is induced by the mitotic spindle during early anaphase.

Detailed explanation-4: -Microtubules of the bipolar spindle dictate the position of the cleavage plane midway between the two asters. Subsequently, microtubules of the spindle midzone promote ingression of the cleavage furrow and the completion of cytokinesis.