MICROANATOMY

Detailed explanation-1: -The ER is composed of one completely continuous membrane bilayer and has a single continuous lumen; the ability of the ER to have differently shaped domains requires some membrane proteins to segregate and form these domains through their assembly. The NE is the most visually obvious domain made from ER membrane.

Detailed explanation-2: -The endoplasmic reticulum (ER) is a network of membrane-enclosed tubules and sacs (cisternae) that extends from the nuclear membrane throughout the cytoplasm (Figure 9.1). The entire endoplasmic reticulum is enclosed by a continuous membrane and is the largest organelle of most eukaryotic cells.

Detailed explanation-3: -Rough endoplasmic reticulum has rough surface due to the presence of ribosome and they are present towards the nucleus and attached with the karyotheca and the membrane of Golgi apparatus. Thus, the correct answer is option D.