MICROANATOMY

Detailed explanation-1: -Endochondral ossification begins with mesenchymal tissue transforming into a cartilage intermediate, which is later replaced by bone and forms the remainder of the axial skeleton and the long bones.

Detailed explanation-2: -Endochondral ossification involves the replacement of hyaline cartilage with bony tissue. Most of the bones of the skeleton are formed in this manner. These bones are called endochondral bones. In this process, the future bones are first formed as hyaline cartilage models.

Detailed explanation-3: -Enchondral bone formation represents bones formed in a hyaline cartilage template. This is the most common method by which bones form. Examples include the femur, tibia, vertebrae, and metacarpals.

Detailed explanation-4: -Endochondral ossification is the process of bone development from hyaline cartilage.

Detailed explanation-5: -During endochondral ossification, an avascular tissue (cartilage) is gradually converted into one of the most highly vascularized tissues in the vertebrate body (bone). This conversion is dependent upon an angiogenic switch along the growth plate.