MICROANATOMY

Detailed explanation-1: -Osteoblasts are bone-forming cell, osteoclasts resorb or break down bone, and osteocytes are mature bone cells.

Detailed explanation-2: -Some of these osteoblasts show cytoplasmic processes towards the bone matrix and reach the osteocyte processes [46]. At this stage, the mature osteoblasts can undergo apoptosis or become osteocytes or bone lining cells [47, 48].

Detailed explanation-3: -Osteocytes are cells lying within the bone itself and are ‘entrapped’ osteoblasts. They are post-proliferative, representing the most mature differentiation state of osteoblast lineage. There are about 25, 000 osteocytes per mm3 of bone.

Detailed explanation-4: -Osteocytes are stellate-shaped cells within the mineralized bone matrix that comprise 90-95% of all bone cells, therefore, they are the most abundant bone cell in the adult skeleton.