PATHOLOGY

PATHOLOGY MCQ

CELL DAMAGE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A mutation is least likely to affect a cell when the mutation-
A
reverses the order of bases in a DNA strand
B
allows the total number of bases in a DNA sequence to remain the same
C
replaces a base with its complementary base
D
produces a triplet that codes for the same amino acid as the original triplet
Explanation: 

Detailed explanation-1: -Silent mutations are least likely to affect protein function. Missense mutations are often difficult to predict. If the change is to a similar amino acid or in a non-critical amino acid, the mutation protein may continue to function.

Detailed explanation-2: -The correct answer is (c) substitution. A substitution mutation occurs when one nucleotide is exchanged for another in the DNA sequence. This would not shift the gene sequence forward or backward, and so a maximum of one amino acid would be altered in the protein.

Detailed explanation-3: -Missense Mutation A missense mutation is a DNA change that results in different amino acids being encoded at a particular position in the resulting protein.

Detailed explanation-4: -So, the correct option is ‘A missense substitution’

There is 1 question to complete.