PATHOLOGY MCQ
GENETICS AND DISEASE
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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to cure genetic diseases
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to understand genetic diseases
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to identify all genes in all 46 chromosomes
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to identify all genes in all 23 chromosomes
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Detailed explanation-1: -There are a number of well-recognized ethical concerns about large-scale genomic biorepositories, including (1) the initial consent process, (2) concerns about privacy and confidentiality, and (3) reconsent for further studies or at the time when a child turns 18 years old.
Detailed explanation-2: -Ethical issues known to be associated with genomic research in general, such as privacy risks and informed consent/assent, seem especially pressing for NDD participants because of their potentially decreased cognitive abilities, increased vulnerability, and stigma associated with mental health problems.
Detailed explanation-3: -ChIP-PCR is performed to analyze histone modifications and/or protein binding to a known subset of target loci in the genome. In ChIP-PCR, immune-enriched DNA fragments are identified and quantified using widely available PCR or qPCR reagents and technologies.
Detailed explanation-4: -When the genomic data are publicly accessible, there is a risk of discrimination during enrollment for a job or obtaining health insurance. Individuals could be denied a job or an insurance policy based on the genetic information which suggests the risk of susceptibility to any chronic disease or cancer.