PATHOLOGY

Detailed explanation-1: -People who have Marfan syndrome can have weak tissue in their heart valves. This can produce stretching of the valve tissue and abnormal valve function. When heart valves don’t work properly, your heart often has to work harder to compensate. This can eventually lead to heart failure.

Detailed explanation-2: -Marfan syndrome can damage the blood vessels, heart, eyes, skin, lungs, and the bones of the hips, spine, feet, and rib cage. Some complications of Marfan syndrome can be treated or prevented, including heart disease, bone deformities such as a curved spine, eye conditions, crooked teeth, and collapsed lungs.

Detailed explanation-3: -The heart muscle may enlarge and weaken over time, causing cardiomyopathy, even if the heart valves are not leaking. The condition may progress to heart failure. Abnormal heart rhythm. Arrhythmia can occur in some people with Marfan syndrome.