PATHOLOGY MCQ
INFLAMMATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Activated T-cells release IFN- to induce an inflammatory activated macrophage stimulating ROS, proteases and cytokines. Whilst other cells that release IL-4 induce a repair activated macrophage to secrete growth factors and remodelling collagenases
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True
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False
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Either A or B
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None of the above
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Explanation:
Detailed explanation-1: -When macrophages are exposed to inflammatory stimuli, they secrete cytokines such as tumor necrosis factor (TNF), IL-1, IL-6, IL-8, and IL-12. Although monocytes and macrophages are the main sources of these cytokines, they are also produced by activated lymphocytes, endothelial cells, and fibroblasts.
Detailed explanation-2: -The activation and proliferation of CAR-T cells release primary cytokines such as IL1, IFN-, and TNF, which induce the activation of other immune cells, such as macrophages, DCs, and monocytes (241). These cells then produce excessive amounts of secondary cytokines, such as IL6, IL10, and IL5 (242).
There is 1 question to complete.