ANTIGENS
ANTIGENS AND IMMUNOGENICITY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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CLASS II ASSOCIATED INVARIANT CHAIN PEPTIDE
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CLASS III ASSOCIATED INVARIANT CHAIN PEPTIDE
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CLASS I ASSOCIATED INVARIANT CHAIN PEPTIDE
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COMMON INVARIANT CHAIN PEPTIDE
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Detailed explanation-1: -CLIP or Class II-associated invariant chain peptide is the part of the invariant chain (Ii) that binds to the peptide binding groove of MHC class II and remains there until the MHC receptor is fully assembled. CLIP is one of the most prevalent self peptides found in the thymic cortex of most antigen-presenting cells .
Detailed explanation-2: -The invariant chain (Ii) prevents binding of ligands to major histocompatibility complex (MHC) class II molecules in the endoplasmic reticulum and during intracellular transport.
Detailed explanation-3: -MHC class II molecules are heterodimers composed of two noncovalently joined transmembrane glycoproteins, and . Each chain has two domains. The 1 and 1 domains together form the peptide-binding cleft.