ANTIGENS
ANTIGENS AND IMMUNOGENICITY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Monomer
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Dimer
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Trimer
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Pentamer
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Detailed explanation-1: -Abstract. Soluble immunoglobulin M (IgM) forms a pentamer containing a joining (J) chain polypeptide. While IgM pentamer has various immune functions, it also behaves as a carrier of circulating apoptosis inhibitor of macrophage (AIM; also called CD5L) protein that facilitates repair during different diseases.
Detailed explanation-2: -Other human IgM polymers include the tetramer (2, L2)4 and the hexamer (2, L2)6, with the hexamer being the most frequent polymer after the pentamer. IgM are present as pentamers throughout the vertebrate evolutionary ladder, from the less evolved bony fishes (Osteichthyes) to mammalians.
Detailed explanation-3: -As a B-cell surface immunoglobulin, IgM exists as a monomer and functions as a receptor for antigens.